According to the Solvophobic Theory a variation of pH, temperature, gradient time/ %B value, or ternary eluent composition makes a continuous variation of the selectivity possible. The comprehension and assignment of peaks from a set of systematic experiments is an important first step to control the development process of an HPLC method. PeakMatch® helps the user to keep survey of his work by offering four main functions: First Function: PeakMatch® structures your experiments and takes care of the documentation, comparison and recognition of the key influences and the method as a whole. The chromatograms and the peak table are displayed completely on one page, which facilitates the overview of the complex data. Cell colours imply a good (green), questionable (blue) and false (red) peak assignment.

Second Function: A false assignment of identical peaks in between experiments is a common reason for wrong DryLab® models. Therefore the goal of peak matching is to set the areas of identical peaks of the basic runs in a way that they all end up standing in the same horizontal line. Peak tracking means to adjust the order of the peaks in the table in a way, that they all correspond correctly to each other. Only then, the correct data-transfer into DryLab® is possible. PeakMatch® helps you to bring order into your experiments: Weather it is cutting up double peaks, re-arranging turnover peaks or reducing general complexity, zooming into relevant peak areas and/ or deleting irrelevant bands, PeakMatch® offers you useful functions to prepare your peak table in the best possible way!

Third Function: PeakMatch® transfers all collected data (peak table with retention times, peak areas, eluents, flowrate, column length, column diameter, particle size, gradient range, etc.) into DryLab® with only one mouseclick. Within a few seconds DryLab® then simulates a model. The simple adjustment of the peak table and the following transfer of the peak data into DryLab® are important reasons for the success of PeakMatch®.

Fourth Function: By comparing the calculated DryLab® model with the original experiments, PeakMatch® validates the virtual model. If simulations and experiments don't correspond, the match is defective and the peak table has to be adjusted further. The quality of pharmaceutical products is always approved by HPLC methods. A secure and robust method is therefore a necessary component of the production process. PeakMatch® and DryLab® help to achieve this aim. They help to structure and organize your work, save time and material for runs and make the laboratory work more predictable, satisfactory and successfull.