Robuste HPLC - English

DryLab® + PeakMatch® -user course for HPLC

Place:
Berlin
Course goals:
In this course you will learn the principles and techniques for the development of robust HPLC Methods. The course will be held in english language.
You will receive a practical course manuscript and a CD of an HPLC teaching software with the exercizes used in the course and with other typical examples of HPLC method development.
Target group:
Pharmacists, chemists and members of R&D or quality control in the pharmaceutical, chemical and food industry.
The course will be hold by Dr. Imre Molnar:
Dr. Molnar studied chemistry in Saarbrücken with special training in analytical chemistry. He then worked for two years as a post-doctoral fellow with Csaba Horváth at Yale University, USA, on fundamentals of Reversed Phase Chromatography. He has 20 years of experience in the development of HPLC-instruments, column production and HPLC applications and spezializes in pharmaceutical and biopolymer research and analysis. For nearly the same time he is working as a trainer for HPLC. Since 1986 there is a close cooperation with Lloyd R. Snyder, John Dolan and co-workers from LC Resources.Inc. USA, for the joint development of the DryLab-Software.

Program

Which are the chromatographic prerequisites in the development of an efficient HPLC-method?
Which are the promising parameters to optimize? Why are robust methods before the validation process so important?

How to select suitable input runs for systematic development of HPLC-methods? Use of DryLab® with different experimental
designs How many input runs are needed by DryLab®? How can I use DryLab® to make my methods more robust?

Organization of experimental data and peak tracking with PeakMatch® Correction of peak overlaps and reversed elution
orders Elimination of non-relevant peaks from the peak table

How to create a DryLab® model of the separation and how to find out the strengths and weaknesses and how to define the quality
of an HPLC-method

Evaluating the DryLab model - Finding optimum conditions for final method Gradient optimization - how does the selectivity
change in method transfer?
Optimization of column dimensions and flow rate (speeding up method)

Participation fee
The cost of participation for two days is EUR 1.490,- . If you register 6 weeks in advance the cost will be EUR 1.340,- .
Bank account
Berliner Sparkasse (BLZ 100 500 00), Konto-Nr. 6 5000 7000
IBAN: DE51 1005 0650 0070 00, BIC/SWIFT-Code: BELADEBE
Remark: HPLC-Course in Berlin, and your name
Registration
Registration by e-mail:
info@molnar-institut.com

or fill in registration form, and send it back to:

Molnar-Institut für angewandte Chromatographie
Schneeglöckchenstr. 47
D-10407 Berlin
tel.: +49-30-421-559-0
fax: +49-30-421-559-99