Course Dates

Exhibitions

Software Release Notes

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Copyright 2010
Molnar-Institute
All rights reserved

Method Design
You have a complex mixture of which an HPLC-method has to be developed immediately? You want the method to have a short run time, to be robust and economical but you expect weeks or even months of work to spend on this task? Resources are used and other projects must wait while valuable time is wasted?

For those who know such situations we offer two procedures:

A.
We develop the method with your experiments. You send us 4 runs with your sample (no names needed) prepared according to the attached guide
 (PDF) and we develop a model representing approximately 10.000 precise predictions.

B. You send us your sample and we develop a state of the art method with DryLab® for you in Berlin.


We deliver

  • All necessary peak tracking
  • Input of experimental results into DryLab®
  • Development of a model for your mixture with a buffer (Eluent A) against Acetonitril or Methanol (Eluent B)
    • Gradient vs. temperature model (4 reproducible input runs with a factor 3 in steepness- and 30°C difference in temp.) or
    • Isocratic: %B vs. temperature model (4 reproducible input runs: 20%B- and 30°C difference) or
    • Gradient vs. pH-value model (6 reproducible input runs with 3 pH-values with a difference of 0.5 pH, each at two gradient times) or
    • Isocratic: %B vs. pH model (6 reproducible input runs with 20% difference in B, and 3 pH-values 0.5 units difference)
  • Proof of robustness
  • Method development report.

Of course, we are open to discuss other options and possible aproaches.

11 Nov 2010
HPLC DryLab User Course
16 Sep 2010
HPLC User Course (German)
10 Jun 2010
HPLC DryLab User Course
22 Apr 2010
HPLC User Course (German)
30 Mär 2010
Latest Developments in DryLab® 2010 v. 3.9
28 Feb 2010
Pittsburgh Conference in Orlando
29 Jun 2009
Pharmaceutical Optimization
28 Jun 2009
HPLC2009, Dresden
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